Yes, these were successes, but the successes could have been bigger if we had really paid attention to marketing. What's even worse is that a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die. Still, in the moment, his question threw me, and I stuttered. Links to evidence about fluvoxamine including the public data repository. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. The race to find covid-19 drug treatments that actually work, The antimalarial drug Trump took for covid might actually be dangerous. Should you get vaccinated? Steve Kirsch | TrialSite News It was so bad you couldnt even see the babys body through all the blood, Kirsch said. If you wanna find someone to debate me for ten thousand dollars, or a thousand dollars, Im happy to do that, just for your benefit.. Those who know Kirsch say this is a typical tactic. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. An approach that promised to democratize design may have done the opposite. We look for advances that will have a big impact on our lives and break down why they matter. Unfortunately, as Jeffrey Morris at UPenn points out, public health officials and scientists have done plenty to undermine their own authority, like claiming masks dont work, downplaying the natural immunity conveyed by previous covid infections, and not doing enough public communication about vaccine safety surveillance systems. Fluvoxamine was reportedly added to just 2 practice guidelines (Ontario and Johns Hopkins). . It used to be that a Phase 3 study would do it. My website www.skirsch.io has tons of info on fluvoxamine with all the links. In 2013, Johnson & Johnson paid $2.2 billion for its own kickback and fraud scandal, including a specific $400 million fine for its subsidiary Janssen, which manufactures the covid vaccine. Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? They knew in advance it was coming and on the day the paper was published they ignored it entirely. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here.. Los Altos Hills resident touts fluvoxamine as COVID-19 treatment Fluvoxamine: A Review of Its Mechanism of Action and Its Role - PubMed When was the last time you saw a phase 3 fail where there was a 100% effect size in both an RCT and RWE study along with 4 independent observational trials all showing a positive effect, and there is clear mechanism of action where there is less than a 1% chance that it is not working (the SSRI's ordered their impact based on their Sigma activation which is 1 in 120 options), and where in every single case we are aware of the patient taking the drug reversed to normal in an average of 3 days? He is very smart, and he knows that he is very smart, and hesometimes he behaves like he thinks hes the smartest guy in the room, whether he is or isnt, he told me. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. BOMBSHELL: Top biostats professor admits we have NO CLUE # of people KILLED by COVID vaccines, he wrote. While YouTube has repeatedly taken down the full video of the DarkHorse episode, various clips have been watched over 4 million times, and the full audio remains available on Spotify. Proven in clinical use all over the world. Once the Phase 2 result came out, it should have been embraced by doctors. This post was written to memorialize the corruption. So much for evidence-based medicine. . We pretty much practice government agency opinion medicine all over the world now, with just a few exceptions. Everyone is stunned, but nobody is surprised. There are 4 outpatient studies that have been done (2 at WashU (see Phase 2 trial results published in JAMA), one in Berkeley, CA by David Seftel, one in Brazil published in the Lancet, and one in-patient study done in Croatia. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). In October, the group reported that, while a few patients in the placebo group ended up in the hospital, none of the patients receiving fluvoxamine got sick enough to go. Over the summer, the conflict reached his most recent startup, M10. No long haul symptoms if you start the drug ASAP after first symptoms. Its board told him that if he wanted to remain part of the company he would have to stop making public anti-vaccine statements. As a health care journalist, I started off firmly in the wait-and-see camp on mRNA vaccines. He wrote on his personal website that hed been advised that being associated with the drug would immediately trash my credibility.. Steve wanted to say, Look, Ive got all these famous [infectious disease] docs and researchers, and they all say give fluvoxamine a chance, Judith Feinberg, one of the former CETF advisory board members and vice chair of research at the West Virginia University School of Medicine, told me. customer-service@technologyreview.com with a list of newsletters youd like to receive. This is the gold standard of evidence based medicine. Please, As of November 13, fluvoxamine has been proven to work in every trial that has published results, including, studies. As noted before, the repository has a link to the 1 hour serotonin lecture. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. Most recent articles first. We are ignoring the advice of the KOL group and doing nothing. Hes probably the closest thing Kirsch has to a nemesis, regularly disputing his assertions in blog posts and private email exchanges with Kirsch and his friends. Perhaps Kirschs most effective tactic, though, is simply his willingness to outlast everyone else. Physicians who use the drug for COVID now swear by it. The results would, eventually, set Kirsch on a collision course with the scientific establishment. Fluvoxamine is used commonly to treat obsessive-compulsive disorder (OCD), social anxiety disorder and depression. In some cases, youd want to taper down the dosage. The NIH wrote a bullshit rejection because the FDA told them not to approve it. Steve and CETF funded the research that showed promising results of fluvoxamine as an early treatment of COVID-19. Medium banned him for misinformation. Their willingness to lie did. Elsewhere he has said he began questioning vaccine safety after an unnamed Twitter follower told him several family members died after getting their shots. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. But they will refuse to give it to you even after being proven in a Phase 3 trial that was approved by the WHO. Substitutions. You see this with people who have a lot of money, who think that reflects their intelligence, Richman told me. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. Online. Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. For decades, coders wrote critical systems in C and C++. (The ivermectin data are trash, Feinberg told me. None of this would really matter if Kirschs views on vaccinations were private, or shared with a limited audience. Thats why they didnt even fund the fluvoxamine trial, he told me. There were no studies reported out so far where fluvoxamine made things worse or neutral. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. has tons of info on fluvoxamine with all the links. It was tested in coronavirus patients because fluvoxamine has very strong anti-inflammatory properties. So when a group of scientists applied for an EUA for fluvoxamine, what did the FDA do? How the FDA justified rejecting an EUA for fluvoxamine [4] Steve Kirsch - Silicon Valley Philanthropist Shares Review of CDC Data: COVID-19 Vaccine Associated with 100X Deaths Compared to Influenzas [5] Steve Kirsch - FOIA Document for Vaccine Discussion as to mRNA-based Vaccine Safety Signals Added 12th August 2021: Steve Kirsch (@stkirsch) / Twitter - Twitter. It's what's happening Today, if we follow the CDC advice, nearly 100,000 people a month will die from COVID. There were no studies reported out so far where fluvoxamine made things worse or neutral. The medical community doesnt care about saving lives. From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). This is the #1 ranked best answer to "COVID treatment" on Quora: Presentation on how fear of trying something new is what keeps us shutdown and leads to unnecessary loss of life: The Lenze fluvoxamine RCT that was published in JAMA on November 12, 2020 showed a 100% success rate in preventing hospitalization. Some are views most scientists think are wrong. The effect size is huge if the drug is given early right after symptoms start. @stkirsch. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. just like ivermectin). Other SSRIs work as well, but fluvoxamine activates the Sigma-1 receptor the most of the SSRIs which is why it was chosen. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. Other SSRIs work as well, but fluvoxamine activates the Sigma-1 receptor the most of the SSRIs which is why it was chosen. This drug can save your life but you have to ask for it! In short, a lot of mumbo jumbo. The board members I spoke to say they refused to publicly promote any drugs for off-label use and tried to explain to Kirsch that its incredibly common for exciting results from small trials to disappear in larger ones. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. As of January 18, 2021, the CDC estimates that 90,000 Americans will die from COVID in just the next 3 weeks. Part of TV News Archive. Don't underestimate the virus. In the second trial, it was shown to be 100% effective in long-haul COVID symptoms: None of the treated patients had any long-haul symptoms after 2 weeks compared to 60% of untreated patients having 1 or more of the 15 long-haul symptoms after two weeks, and 29% having 4 of more of the long haul symptoms after 2 weeks. . I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. If you start later, doctors use higher dosages and compliance becomes a bigger problem. A few months ago, Kirsch suddenly stopped promoting hydroxychloroquineeven scrubbing it from the CETFs official list of trials it has funded. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. If you cant get a prescription for COVID, then perhaps you have OCD? He is the inventor of the optical mouse and one of the first Internet search engines, Infoseek. Note: normally I have lots of hyperlinks to all the sources, but Im pressed for time. The NIH Guidelines committee is being very slow to react (we have no idea if they are even considering the drug because nobody is allowed to know that because all their deliberations are kept secret). My favorite dosage is 50mg twice a day for 14 days. While combining the results of several well-designed trials can strengthen an argument or unearth patterns unseen in smaller samples, a meta-analysis is just the sum of its parts; any single well-done experiment is more useful than combining the results of several poorly done ones. If you start later, doctors use higher dosages and compliance becomes a bigger problem. MD, MPH; Steven C. Marcus, PhD. Drug interactions should be checked for. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. Some people report mild nausea while on the drug (stops when stop the drug). All the supporting observational studies were positive as well. If you cant lay off the java, then try fluoxetine (Prozac). If you continue to get this message, The alarming article cited the claims of two anti-vaxxers, Steve Kirsch and Dr. Robert Malone. They all promised me when fluvoxamine passed Phase 3 trials, nearly everyone would use it. Steve calls himself a "medical philanthropist" who says "the most important thing to me is saving lives." In . Everyone says "we need more data" to show fluvoxamine works for COVID. I was just getting tired, he said, before asking to speak off the record. And, according to three members of CETFs scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for covid. Fluvoxamine has a 40 year safety track record. Our in-depth reporting reveals whats going on now to prepare you for whats coming next. He has made millions from these projects, even if they have not turned him into a household name. That way you can start immediately. Government agencies are ignoring the science. That receptor also helps regulate the body's . That was a lie. Stopping the meds will return you to your normal self. Try refreshing this page and updating them one He may not be a good scientist, but hes smart, says WVUs Feinberg. Steve Kirsch and Dr. Robert Malone, MIT COVID-19 Postgame - Substack Share this post.
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